What are the side effects of stopping Amlodipine abruptly?

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 Amlodipine is a calcium channel blocker medication. Amlodipine and Norvasc are the brand names for these pharmaceuticals. Amlodipine is frequently used in combination with other blood pressure medications. So, in addition to the brand-name drug, it could be mixed with other ingredients in the same pill. It is available in tablet form as well as an oral suspension (Katerzia).


When used as directed, amlodipine is completely safe. However, before taking this medication, you should consult with your doctor. That is why they are not available over the counter.

Amlodipine and other calcium channel blockers are used to treat high blood pressure. They may also lower the risk of angina and cardiovascular complications (heart attack, stroke). To control blood pressure, it can be combined with a diuretic and other medication. 

What negative side effects may result from stopping amlodipine? 

When used correctly, amlodipine is a safe medication. However, stopping the drug or discontinuing amlodipine can have serious side effects. They are more common if you have congestive heart failure or liver disease. Stopping amlodipine can have additional side effects in the elderly.

Below are some examples of the effect of stopping amlodipine abruptly as follows: 

1. Rebound high blood pressure

The most serious adverse effect of stopping amlodipine is an increase in blood pressure measurements. This medication is prescribed to patients who have high blood pressure. Stopping their treatment returns to the problem that the drug was treating. Not all patients will experience symptoms when their hypertension returns. Rebound hypertension does not always manifest as symptom. Instead of relying on your feelings, monitoring your blood pressure is critical to avoiding this problem.

2. Chest aches

Amlodipine is commonly prescribed to patients suffering from hypertension and angina. The latter is a type of heart disease that causes chest pain by constricting the coronary arteries and decreasing blood flow to the cardiac muscle. With insufficient oxygen supply, the cardiac muscle suffers, resulting in chest pain. Nitroglycerin can be used to treat angina. Amlodipine, on the other hand, alleviates the symptom by relaxing the blood vessels. As a result, if you stop taking amlodipine, your angina symptoms may return or worsen because your oxygen requirements are no longer met. Some people may not experience this side effect.

Discontinuing amlodipine worsens angina in patients with heart disease because their coronary arteries spasm suddenly (vasospastic angina). The above-mentioned side effects of stopping amlodipine can be divided into two categories.

1. Some are caused by an underlying condition that amlodipine was prescribed to treat. Others are caused by changes in your organism's response to hemodynamic changes. A return to the baseline condition causes the majority of side effects.

2. The dizziness and headaches will subside after a few weeks as your body adjusts to the hemodynamic changes.

Amlodipine withdrawal symptoms are not considered a withdrawal syndrome, as is the case with opioid medications and other drugs that cause tolerance. They are caused primarily by a return to the baseline disease.

They differ from the classic medicine withdrawal syndrome in this regard, which features new symptoms that are not explained by a baseline disease. Some studies, however, have described a type of withdrawal syndrome following the discontinuation of antihypertensive drug therapy. It occurs in a very small number of people and is considered extremely rare.

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